Gene Therapy for Ophthalmic Diseases
نویسندگان
چکیده
In the field of ophthalmology, gene therapy has focused on hereditary retinal dystrophy, including retinitis pigmentosa. Hereditary dystrophy is a group intractable diseases for which there currently no effective treatment, and expectations are regeneration using iPS cells. recent years, results number clinical trials therapies have been reported from Europe United States. Since 2017, drugs Leber congenital amaurosis approved after being found to be safe therapeutically efficacious. this article, we will discuss current state pigmentosa use adeno-associated virus (AAV) vectors in therapy.
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ژورنال
عنوان ژورنال: Nihon Ika Daigaku Igakkai Zasshi
سال: 2023
ISSN: ['1349-8975', '1880-2877']
DOI: https://doi.org/10.1272/manms.19.242